CHEMGATE: VQE COST OPTIMIZER
Lower quantum chemistry compute costs without sacrificing accuracy. Typically 30-40% cost reduction on real drug molecule workloads, validated on IBM Heron hardware.
WHAT CHEMGATE DELIVERS
Fewer quantum hardware computations per VQE iteration with zero accuracy loss
Validated on real pharmaceutical molecules up to 16 qubits
Built-in accuracy guarantees with automatic recovery when needed
Tested on IBM Fez and Rigetti Ankaa-3 with real quantum hardware noise
IBM FEZ HARDWARE VALIDATION
Caffeine
8
Computations evaluated
Evaluated: 53%
COMMERCIAL VALUE
32-42% fewer evaluations
Each evaluation costs real QPU time. ChemGate reduces computation cost.
Fail-safe by design
Guaranteed accuracy with automatic recovery. Best case: save 44% of evaluation cost.
Real drug molecule validation
Validated across multiple drug molecules with ab initio reference energies.
Complements other optimization approaches
Complements shot reduction methods. Evaluation reduction × shot reduction.
VALIDATED RESULTS SUMMARY
| MOLECULE | QUBITS | SAVINGS | BACKEND |
|---|---|---|---|
| Caffeine | 8 | 32% | IBM Fez |
| Warfarin | 16 | 41% | Simulation |
| Metformin | 16 | 44% | Simulation |
| Penicillin V | 16 | 44% | Simulation |
All Hamiltonians: ab initio with validated geometries. No synthetic data.
METHODOLOGY
SIMULATION
Simulation with classical optimizer. Paired episodes per molecule. Statistical significance validated.
HARDWARE (MODE A)
Final optimized circuits from simulation submitted to IBM Fez. Real hardware energy measurement.
HAMILTONIANS
All drug molecules generated via standard computational chemistry pipelines. Ab initio reference energies. Zero synthetic data.